BioNTech has established a broad set of relationships with multiple global pharmaceutical collaborators, including Genmab, Sanofi, Bayer Animal Health, Genentech, a member of the Roche Group, Regeneron, Genevant, Fosun Pharma, and Pfizer. [Updated 7/6/2020] The Recent Moderna Selloff. [email protected], BioNTech: Are treatments, vaccines or testing stocks the best way to play the coronavirus recovery? Pfizer shares traded 9% higher to a new 52-week high price after the company reported that interim data from its Phase 3 COVID-19 vaccine trial with BioNTech showed a 90% success rate in participants without prior evidence of SARS-CoV-2 infection. Opinions expressed by Forbes Contributors are their own. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. “With hundreds of thousands of people around the globe infected every day, we urgently need to get a safe and effective vaccine to the world.”, “We are grateful that the first global trial to reach the final efficacy analysis mark indicates that a high rate of protection against COVID-19 can be achieved very fast after the first 30 µg dose, underscoring the power of BNT162 in providing early protection,” said Ugur Sahin, M.D., CEO and Co-founder of BioNTech. Among children in the older age group, there was an increased risk of febrile seizures within 7 days after any of the vaccine doses. For instance, the potential addressable market for a vaccine could stand at 7.5+ billion (the worldwide population) versus ~2.5 million currently for potential coronavirus therapeutics. So how do the Moderna and Oxford-AstraZeneca vaccines’ developments compare? [Updated 6/2/2020] Moderna Moves To Crucial Phase 2 Trials. Moderna (NASDAQ: MRNA) stock has declined by close to 10% over the last two trading days. They can be used be as temporary storage units for 15 days by refilling with dry ice. Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced that, after conducting the final efficacy analysis in their ongoing Phase 3 study, their mRNA-based COVID-19 vaccine candidate, BNT162b2, met all of the study’s primary efficacy endpoints. The Company exploits a wide array of computational discovery and therapeutic drug platforms for the rapid development of novel biopharmaceuticals. This is ahead of the fall timeline previously anticipated for phase 3 trials. Early results from trials of a Covid vaccine developed in Russia suggest it could be 92% effective. Epub 2012 Jul 25. Amy Rose CID 2012; 55(7):951-959. Pharma bellwether Johnson & Johnson’s vaccine is expected to start phase 1/2a trials over the second half of July. Phase 1 trials usually involve a few dozen people and are designed to observe whether a vaccine or drug is safe. The Phase 3 clinical trial of BNT162b2 began on July 27 and has enrolled 43,661 participants to date, 41,135 of whom have received a second dose of the vaccine candidate as of November 13, 2020. For more information, please visit www.BioNTech.de. One of the biggest challenges in estimating the success rate of clinical trials is a… While the markets have tumbled due to the spread of the novel coronavirus, stocks of pharma companies developing vaccines and treatments for the highly contagious viral infection have fared well. Approximately 42% of global participants and 30% of U.S. participants have racially and ethnically diverse backgrounds, and 41% of global and 45% of U.S. participants are 56-85 years of age. Analysis of the data indicates a vaccine efficacy rate of 95% (p<0.0001) in participants without prior SARS-CoV-2 infection (first primary objective) and also in participants with and without prior SARS-CoV-2 infection (second primary objective), in each case measured from 7 days after the second dose. Pharmaceutical manufacturer Johnson & Johnson announced Friday that early trials of a COVID-19 vaccine showed a 98 percent success rate in showing a … View source version on businesswire.com: https://www.businesswire.com/news/home/20201118005595/en/, Pfizer: See all Trefis Price Estimates and Download Trefis Data here, What’s behind Trefis? The probability of FDA approval after submitting a New Drug Application (NDA) or Biologic License Application (BLA), taking The trial will continue to collect efficacy and safety data in participants for an additional two years. 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