pulmonol in pregnancy

2020 Nov 17 [Epub ahead of print]. Guidance: paediatric multisystem inflammatory syndrome temporally associated with COVID-19. Carfì A, Bernabei R, Landi F, et al. Clerkin KJ, Fried JA, Raikhelkar J, et al. Novel paediatric presentation of COVID-19 with ARDS and cytokine storm syndrome without respiratory symptoms. http://www.ncbi.nlm.nih.gov/pubmed/32362244?tool=bestpractice.com, Guillain-Barre syndrome has been reported. Even before pregnancy, cigarette smoking is of influence since it is dose dependently associated with a decrease in fertility. Intensive Care Med. 2020 May 14;41(19):1798-800. https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaa231/5809453, http://www.ncbi.nlm.nih.gov/pubmed/32186331?tool=bestpractice.com. Definition: signs and symptoms that develop during or after an infection consistent with COVID-19, continue for more than 12 weeks, and are not explained by an alternative diagnosis. http://www.ncbi.nlm.nih.gov/pubmed/32247022?tool=bestpractice.com Find a Pulmonologist near you in your state. http://www.ncbi.nlm.nih.gov/pubmed/32179124?tool=bestpractice.com, Guidelines for the management of shock in critically ill patients with COVID-19 recommend a conservative fluid strategy (crystalloids preferred over colloids) and a vasoactive agent. https://covid19treatmentguidelines.nih.gov/ One study found that patients with COVID-19 were more likely to develop gastrointestinal complications compared with those without COVID-19, specifically transaminitis, severe ileus, and mesenteric ischaemia. Belen-Apak FB, Sarıalioğlu F. Pulmonary intravascular coagulation in COVID-19: possible pathogenesis and recommendations on anticoagulant/thrombolytic therapy. Wang T, Chen R, Liu C, et al. [1027]Leisman DE, Ronner L, Pinotti R, et al. Patterns of allergic sensitization and atopic dermatitis from 1 to 3 years: effects on allergic diseases. Dharma C, Lefebvre DL, Lu Z, Lou WYW, Becker AB, Mandhane PJ, et al. The mortality rate was 1.9%. Valverde I, Singh Y, Sanchez-de-Toledo J, et al. [3]National Institutes of Health. 2020 Nov 17 [Epub ahead of print]. [1032]Royal College of Paediatrics and Child Health. https://jamanetwork.com/journals/jama/fullarticle/2768715 [17]Swann OV, Holden KA, Turtle L, et al. The risk to have a child who is a carrier like the parents is 50% with each pregnancy. https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25948, http://www.ncbi.nlm.nih.gov/pubmed/32343429?tool=bestpractice.com. The syndrome has a strong temporal association with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Dobutamine is recommended in patients who show evidence of persistent hypoperfusion despite adequate fluid loading and the use of vasopressors. Arthritis Rheumatol. Wichmann D, Sperhake JP, Lütgehetmann M, et al. https://onlinelibrary.wiley.com/doi/abs/10.1002/art.41425, http://www.ncbi.nlm.nih.gov/pubmed/32602200?tool=bestpractice.com. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202828/ Arrandale VH, Brauer M, Brook JR, Brunekreef B, Gold DR, London SJ, et al. J Thromb Haemost. Parks J, McCandless L, Dharma C, Brook J, Turvey SE, Mandhane P, et al. Sabatino J, De Rosa S, Di Salvo G, et al. Front. Description and proposed management of the acute COVID-19 cardiovascular syndrome. Gubatan J, Levitte S, Patel A, et al. Workman CE, Becker AB, Azad MB, Moraes TJ, Mandhane PJ, Turvey SE, et al. Pulmonol., 23: 111–112. Curr Dev Nutr. Gastrointestinal complications in critically ill patients with and without COVID-19. Brief report: anti-phospholipid antibodies in critically ill patients with coronavirus disease 2019 (COVID-19). 2020 Sep 19:1-11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501509/, http://www.ncbi.nlm.nih.gov/pubmed/32984764?tool=bestpractice.com. Kidney Int Rep. 2020 May 4;5(6):759-61. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196556/, http://www.ncbi.nlm.nih.gov/pubmed/32368701?tool=bestpractice.com. Panda PK, Sharawat IK, Panda P, et al. Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2: a systematic review. Lancet Child Adolesc Health. Graham C, Chooniedass R, Stefura WP, Becker AB, Sears MR, Turvey SE, et al. https://www.nature.com/articles/s41591-020-1054-6, http://www.ncbi.nlm.nih.gov/pubmed/32812012?tool=bestpractice.com. Other symptoms included conjunctivitis (57%), rash (59%), and oral mucosal changes (42%). First case of COVID-19 complicated with fulminant myocarditis: a case report and insights. Press releases, CHILD awarded $1.7M to study impacts of COVID-19 on Canadian families. Coronaviruses and the cardiovascular system: acute and long-term implications. J Neurol. Persistent symptoms 1.5-6 months after COVID-19 in non-hospitalised subjects: a population-based cohort study. 2020 Jul 23 [Epub ahead of print]. Sex-specific impact of asthma during pregnancy on infant gut microbiota. 2018. doi: 10.1016/j.jogc.2018.01.025. Approximately 57% of patients received cardiopulmonary resuscitation. Increasing interleukin-6 levels correlate with increasing fibrinogen levels. Rev Neurol (Paris). Thorax. 2020 May;7(5):e362-3. Stillbirths during the COVID-19 pandemic in England, April-June 2020. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network: United States, March-June 2020. https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaa231/5809453 Assessment of lupus anticoagulant positivity in patients with coronavirus disease 2019 (COVID-19). Ries NM, LeGrandeur J, Caulfield T. Handling ethical, legal and social issues in birth cohort studies involving genetic research: responses from studies in six countries. COVID-19–associated multisystem inflammatory syndrome in children: United States, March–July 2020. Factors associated with the development of myocardial injury include older age, male sex, and the presence of comorbidities. COVID-19–associated multisystem inflammatory syndrome in children: United States, March–July 2020. http://www.ncbi.nlm.nih.gov/pubmed/32297796?tool=bestpractice.com, Myocardial injury has been reported in 20% of hospitalised patients. Maternal morbidity is similar to that of women of reproductive age. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. Wang C, Zhang H, Zhou M, et al. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211496/, http://www.ncbi.nlm.nih.gov/pubmed/32835328?tool=bestpractice.com. Results should be considered in the clinical context. Environ Health Perspect. The estimated background risk of major birth defects and miscarriage for the indicated populations are unknown. J Stroke Cerebrovasc Dis. Jiménez D, García-Sanchez A, Rali P, et al. Description and proposed management of the acute COVID-19 cardiovascular syndrome. Arthritis Rheumatol. Renal dysfunction in hospitalised children with COVID-19. Lancet Gastroenterol Hepatol. 2018. doi: 10.1002/ppul.24063, Miliku K, Robertson B, Sharma AK, Subbarao P, Becker AB, Mandhane PJ, et al. 2018 Jul 30;10(8), Moossavi S, Miliku K, Sepehri S, Khafipour E, Azad MB. Kamal M, Tamana SK, Smithson L, Ding L, Lau A, Chikuma J, et al. JAMA. 2020 Aug;25:100484. https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30228-5/fulltext, http://www.ncbi.nlm.nih.gov/pubmed/32838240?tool=bestpractice.com. Recognizing COVID-19-related myocarditis: the possible pathophysiology and proposed guideline for diagnosis and management. 2020 Dec 8;73:86-95. https://www.clinicalimaging.org/article/S0899-7071(20)30505-2/fulltext, http://www.ncbi.nlm.nih.gov/pubmed/33341452?tool=bestpractice.com, NHS England: acute kidney injury (AKI) algorithm, NICE COVID-19 rapid guideline: managing the long-term effects of COVID-19, BMJ webinar: long COVID – how to define it and how to manage it. In a small retrospective study, 11% of patients at high risk of venous thromboembolism also had a high risk of bleeding. Infection. Stroke is relatively frequent among hospitalised COVID-19 patients relative to other viral respiratory infections, and has a high risk of in-hospital mortality. 2020 Aug 17 [Epub ahead of print]. Epidemiology of asthma: risk factors for development. Cleve Clin J Med. Koehler P, Bassetti M, Chakrabarti A, et al. 2020 Aug;50(2):278-80. 2020 Apr 28;26(7). Risk factors include older age and male sex. Ann Intern Med. http://www.ncbi.nlm.nih.gov/pubmed/33089477?tool=bestpractice.com We read with interest the comprehensive series presented by Bonnin et al. 2020 Nov 1;106349. These complications can occur on presentation or develop as the severity of illness worsens. Exposure assessment in cohort studies of childhood asthma. [1053]Wang F, Wang H, Fan J, et al. http://www.ncbi.nlm.nih.gov/pubmed/32176772?tool=bestpractice.com Coagulopathy and antiphospholipid antibodies in patients with Covid-19. Prior history of pancreatitis does not appear to be a risk factor for pancreatic inflammation in patients with COVID-19. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. Coronavirus disease 2019 (COVID-19) treatment guidelines. 2020 Feb 15;395(10223):507-13. Breastfeeding Medicine. https://onlinelibrary.wiley.com/doi/10.1002/ppul.25245 The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome. Lancet Haematol. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30628-0/fulltext J Med Virol. Davies P, Evans C, Kanthimathinathan HK, et al. Clinical features and outcome of SARS-CoV-2 infection in neonates: a systematic review. Young TK, Shaw KS, Shah JK, et al. Pancreatic injury in the course of coronavirus disease 2019: a not-so-rare occurrence. https://www.cdc.gov/mmwr/volumes/69/wr/mm6940e1.htm, http://www.ncbi.nlm.nih.gov/pubmed/33031361?tool=bestpractice.com. Lodigiani C, Iapichino G, Carenzo L, et al. Asthma is one of the most common chronic medical conditions that may complicate pregnancy. Caulfield T, Burningham S, Joly Y, Master Z, Shabani M, Borry P, et al. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577367/ ASH guidelines on use of anticoagulation in patients with COVID-19. Stewart DJ, Hartley JC, Johnson M, et al. [972]Bansal A, Kumar A, Patel D, et al. 2020 Aug 5 [Epub ahead of print]. Koleva PT, Kim J-S, Scott JA, Kozyrskyj AL. Approximately 79% of patients required intensive care admission, 63% required inotropic support, 57% required anticoagulation, and 33% required mechanical ventilation. 2020 Aug;25:100446. Acute limb ischaemia in two young, non-atherosclerotic patients with COVID-19. ... Pediatr Pulmonol. 2020 Jul;191:151. Persistent symptoms 1.5-6 months after COVID-19 in non-hospitalised subjects: a population-based cohort study. 2020 May;46(5):846-8. Circulation. However, consumption by breast-feeding mothers may impact the infant's behavior during breast-feeding, causing prolonged attachment to the breast and increased sucking. Cytokine release syndrome has been reported in children, although cases appear to be rare. Diseases. [965]Vulliamy P, Jacob S, Davenport RA. 2020 Jun 15;4(8):e28-9. 2020 Aug 18 [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/32873575?tool=bestpractice.com https://www.nice.org.uk/guidance/ng175 https://www.journalofinfection.com/article/S0163-4453(20)30425-4/pdf, http://www.ncbi.nlm.nih.gov/pubmed/32579984?tool=bestpractice.com. https://www.who.int/news-room/commentaries/detail/multisystem-inflammatory-syndrome-in-children-and-adolescents-with-covid-19 Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection: United Kingdom and United States, March–August 2020. Subbarao P, Mandhane PJ, Sears MR. Asthma: epidemiology, etiology and risk factors. [491]Chen T, Wu D, Chen H, et al. [1016]Mandal S, Barnett J, Brill SE, et al. http://www.ncbi.nlm.nih.gov/pubmed/32371536?tool=bestpractice.com, The European Medicines Agency has started a review of a safety signal to assess reports of acute kidney injury associated with the use of remdesivir in some patients. J Pediatr 2017 190:192-199.e2, Koleva PT, Tun HM, Konya T, Guttman DS, Becker AB, Mandhane PJ, et al. The Prebiotic and Probiotic Properties of Human Milk: Implications for Infant Immune Development and Pediatric Asthma. Wang J, Yang Q, Zhang P, et al. Clinical features and outcome of SARS-CoV-2 infection in neonates: a systematic review. Bridgman SL, Kozyrskyj AL, Scott JA, Becker AB, Azad MB. Program within @mayoclinicgradschool is currently accepting applications! http://www.ncbi.nlm.nih.gov/pubmed/32307014?tool=bestpractice.com https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501509/ Mil Med Res. Am J Respir Crit Care Med. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386170/ https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa272/5807944 COVID-19 associated pulmonary aspergillosis. https://www.nature.com/articles/s41591-020-1054-6 Dopamine is only recommended as an alternative vasopressor in certain patients (e.g., those with a low risk of bradycardia or tachyarrhythmias). Autoimmune haemolytic anaemia associated with COVID-19 infection. BMJ. Cases of arterial thrombosis, cerebral venous thrombosis, and acute limb ischaemia secondary to thrombosis have been reported. Tang N, Bai H, Chen X, et al. http://www.ncbi.nlm.nih.gov/pubmed/32283152?tool=bestpractice.com The Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort study: assessment of environmental exposures. Bhattacharjee S, Banerjee M. Immune thrombocytopenia secondary to COVID-19: a systematic review. http://www.ncbi.nlm.nih.gov/pubmed/32644129?tool=bestpractice.com, The pooled incidence of venous thromboembolism, deep vein thrombosis, and pulmonary embolism among hospitalised patients was 17%, 12%, and 7%, respectively. Life-threatening cardiac tamponade complicating myo-pericarditis in COVID-19. Inflammation in the myocardium can result in myocarditis, heart failure, arrhythmias, acute coronary syndrome, rapid deterioration, and sudden death. http://www.ncbi.nlm.nih.gov/pubmed/32496339?tool=bestpractice.com EXPRESS: stroke in COVID-19 – a systematic review and meta-analysis. Associations between meeting the Canadian 24-Hour Movement Guidelines for the Early Years and behavioral and emotional problems among 3-year-olds. Chen N, Zhou M, Dong X, et al. Drall KM, Tun HM, Morales-Lizcano NP, Konya TB, Guttman DS, Field CJ, et al. COVID-19-associated collapsing glomerulopathy: an emerging entity. Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study. Ranucci M, Ballotta A, Di Dedda U, et al. Recognizing COVID-19-related myocarditis: the possible pathophysiology and proposed guideline for diagnosis and management. Patients are commonly managed with intravenous immunoglobulin, vasopressor support, corticosteroids, immune modulators, anticoagulation, antiplatelet therapy, and respiratory support. COVID-19 rapid guideline: acute myocardial injury. ‘Long-COVID’: a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19. http://www.ncbi.nlm.nih.gov/pubmed/32222812?tool=bestpractice.com 2020 Jul 1;105(7):dgaa276. 2020 Apr 28 [Epub ahead of print]. Alanio A, Dellière S, Fodil S, et al. Pulmonol 120ml Pulmonol 120ml Ccl Rs.80 8940. Common long-term symptoms include persistent cough, low-grade fever, breathlessness, fatigue, pain, chest pain/tightness, palpitations, myalgia, arthralgia, headaches, vision changes, hearing loss, earache, tinnitus, sore throat, loss of taste/smell, impaired mobility, numbness in extremities, dizziness, tremors, memory loss, mood changes, skin rashes, gastrointestinal symptoms, neurocognitive difficulties, sleep disturbances, delirium (older people), and mental health conditions (e.g., anxiety, depression). Takotsubo syndrome in patients with COVID-19: a systematic review of published cases. The review of five papers by Schwartz examined 39 newborns from 38 pregnant women in China, and all of 30 women tested for COVID-19 was found negative. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7577367/ Characteristics and outcomes of patients hospitalized for COVID-19 and cardiac disease in Northern Italy. http://www.ncbi.nlm.nih.gov/pubmed/32787707?tool=bestpractice.com It's a serious condition that can damage the right side of the heart. 2020 Jun;80(6):607-13. Konya T, Koster B, Maughan H, Escobar M, Azad MB, Guttman DS, et al. Clin Infect Dis. http://www.ncbi.nlm.nih.gov/pubmed/32873575?tool=bestpractice.com [971]Prasitlumkum N, Chokesuwattanaskul R, Thongprayoon C, et al. [946]Ranucci M, Ballotta A, Di Dedda U, et al. 2020 Oct 21 [Epub ahead of print]. The syndrome is not thought to be linked to disease severity or specific signs and symptoms during the acute phase of illness. https://www.nejm.org/doi/full/10.1056/NEJMc2007575 Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. The syndrome appears to occur in children who have not manifested the early stages of COVID-19, but appears similar to the later phase of COVID-19 in adults. 2020 Aug 29;29(12):105288. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456266/, http://www.ncbi.nlm.nih.gov/pubmed/32992199?tool=bestpractice.com. Mycoses. Take into account the patient’s level of need and the services involved. Asthma during pregnancy poses a common, increasingly prevalent threat to the health of women and their children. Gastrointestinal complications in critically ill patients with and without COVID-19. Sleep 2018:41, Yasmin F, Tun HM, Konya TB, Guttman DS, Chari RS, Field CJ, et al. Thrombosis in hospitalized patients With COVID-19 in a New York City health system. 2020 Aug 25 [Epub ahead of print]. Lancet. http://www.ncbi.nlm.nih.gov/pubmed/32992199?tool=bestpractice.com Azad MB, Robertson B, Atakora F, Becker AB, Subbarao P, Moraes TJ, et al. Hepatic complications such as acute hepatic injury have been associated with an increased risk of severe disease and mortality. Eur Respir J 2013; 41: 1371-7. 2020 Jun 5;20(1):146. 2020 May 21;382(21):e70. Neurological manifestations in COVID-19: a systematic review and meta-analysis. Risk factors include older age ≥60 years, male sex, and severe infection. https://covid19treatmentguidelines.nih.gov/ Eur Heart J. JAMA Pediatr. In other patients, antiphospholipid antibodies may be transient and disappear within a few weeks. It is also important to consider the influence of potential in utero and early-life exposures, such as maternal prenatal nutritional exposures, obesity and weight gain during pregnancy, maternal psychosocial stress, prenatal antigenic exposures, and infant feeding method, on the development of child asthma . https://www.nice.org.uk/guidance/ng171 Maghera A, Kahlke P, Lau A, Zeng Y, Hoskins C, Corbett T, et al. http://www.ncbi.nlm.nih.gov/pubmed/32278361?tool=bestpractice.com, Antiphospholipid antibodies and lupus anticoagulant have been detected in a small number of critically ill patients. [1012]Tenforde MW, Kim SS, Lindsell CJ, et al. 1993; 16:197–200. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. 2020 Feb 18;192(7):E154-E161. Neurological manifestations in COVID-19: a systematic review and meta-analysis. Ye Q, Wang B, Mao J. Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19. Matern Child Health J. 2020 Sep 8. Pregnancy supplements ; Skin, Nail & Hair Care ; Women's health supplements ; Bone & Jointment Care ; Medical Devices. Front Pediatr. 2020 Jul 7;142(1):68-78. Refer patients with signs or symptoms that could be caused by an acute or life‑threatening complication (e.g., severe hypoxaemia, signs of severe lung disease, cardiac chest pain, multisystem inflammatory syndrome in children) urgently to the relevant acute services. Novel paediatric presentation of COVID-19 with ARDS and cytokine storm syndrome without respiratory symptoms. 2020 Nov 10 [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/33284314?tool=bestpractice.com, Limited low-quality evidence suggests that the risk of infection in neonates is extremely low. 2020 Aug 17 [Epub ahead of print]. Management of post-acute covid-19 in primary care. A personalised, multidisciplinary rehabilitation plan that covers physical, psychological, and psychiatric aspects of rehabilitation is an important part of management. 2020 Mar 27;5(7):1-6. 2020 [internet publication]. 2020 Aug 28 [Epub ahead of print]. Ann Allergy Asthma Immunol. 2020 Jul 9 [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/32579984?tool=bestpractice.com Nielsen CC, Gascon M, Osornio-Vargas AR, Shier C, Guttman DS, Becker AB, et al. https://onlinelibrary.wiley.com/doi/full/10.1111/jth.14854 2020 [internet publication]. http://www.ncbi.nlm.nih.gov/pubmed/32423587?tool=bestpractice.com, The pooled prevalence of hepatic manifestations on admission is: elevated alanine aminotransferase (26.6%); elevated aspartate aminotransferase (37.2%); decreased albumin (45.6%); and elevated total bilirubin (18.2%). [1020]Tang N, Li D, Wang X, et al. The risk for two carrier parents to both pass the defective gene and, therefore, have an affected child is 25% with each pregnancy. Epidemiology: in a study in Italy, nearly 90% of hospitalised patients who recovered from COVID-19 reported persistence of at least one symptom 2 months after discharge. Radiology. http://www.ncbi.nlm.nih.gov/pubmed/33089477?tool=bestpractice.com http://www.ncbi.nlm.nih.gov/pubmed/32343223?tool=bestpractice.com Bilaloglu S, Aphinyanaphongs Y, Jones S, et al. JAMA Cardiol. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. Pediatr Pulmonol. https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.031208 Pancreatic injury patterns in patients with COVID-19 pneumonia. Am J Gastroenterol. There are currently insufficient data to recommend either for or against using therapeutic doses of antithrombotic or thrombolytic agents for COVID-19. BMC Med Res Methodol 2014;14:111. Residential green space and pathways to term birth weight in the Canadian Healthy Infant Longitudinal Development (CHILD) Study. Coronavirus disease 2019 (COVID-19) and cardiovascular disease. An analysis of determinants of hopanes in settled indoor house dust. J Exposure Science Environ Epidemiol 2015;25:580-592. [1029]Abrams JY, Godfred-Cato SE, Oster ME, et al. Impact of cardiovascular risk profile on COVID-19 outcome: a meta-analysis. 2020 Nov 11 [Epub ahead of print]. Cognitive dysfunction affects 30% to 80% of patients. Lancet. https://www.atsjournals.org/doi/pdf/10.1164/rccm.202004-1038LE, http://www.ncbi.nlm.nih.gov/pubmed/32396381?tool=bestpractice.com. Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19: scientific brief. http://www.ncbi.nlm.nih.gov/pubmed/32372336?tool=bestpractice.com 2020 Jun 4;135(23):2033-40. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273827/, http://www.ncbi.nlm.nih.gov/pubmed/32339221?tool=bestpractice.com. Overall mortality in COVID-19 patients with gastrointestinal ischaemia and radiologically evident mesenteric thrombotic occlusion was 38.7% and 40%, retrospectively. Gut microbiota and allergic disease in children. COVID-19 add-on study [999]Restivo DA, Centonze D, Alesina A, et al. Abrams JY, Godfred-Cato SE, Oster ME, et al. J Am Coll Cardiol. Early reports suggest that COVID-19 patients treated in the intensive care unit can present with post-intensive care syndrome, a spectrum of psychiatric, cognitive, and/or physical disability (e.g., muscle weakness, cognitive dysfunction, insomnia, depression, anxiety, post-traumatic stress disorder, delirium, encephalopathy) that affects survivors of critical illness, and persists after the patient has been discharged from the intensive care unit. 2020 Jul 27 [Epub ahead of print]. Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the UK: a multicentre observational study. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7228732/ The Canadian Journal of Psychiatry. Hepatic manifestations and complications of COVID-19: a systematic review and meta-analysis. http://www.ncbi.nlm.nih.gov/pubmed/32007143?tool=bestpractice.com Maternal depressive symptoms linked to reduced fecal Immunoglobulin A concentrations in infants. COVID-19 rapid guideline: acute myocardial injury. Bambuterol Multicentre Study Group. Lancet. Blood. 2020 Nov 9 [Epub ahead of print]. J Bronchology Interv Pulmonol 2014;21(3):271-3. doi: 10.1097/LBR.0000000000000084. Azad MB, Sharma AK, de Souza R, Dolinsky VW, Becker AB, Mandhane PJ, et al. [978]Singh S, Desai R, Gandhi Z, et al. Farkash EA, Wilson AM, Jentzen JM. Kozyrskyj AL, Tun HM, Bridgman SL. 2020 Jun 3 [Epub ahead of print]. United European Gastroenterol J. Zhang Y, Xiao M, Zhang S, et al. 2020 Oct 27;8(4):E40. Cord Blood Hemopoietic Cell Receptor Expression is Associated with Early Life Atopic Risk and Lung Function. 2020 Jun 4;135(23):2033-40. PLoS One. Management of patients with liver derangement during the COVID-19 pandemic: an Asia-Pacific position statement.