The lung and the Upper Respiratory Tract -1. They are all artistically enhanced with visually stunning color, shadow and lighting effects. Rationale: Patients with acute lung injury have impaired function of the lung surfactant system.Prior clinical trials have shown that treatment with exogenous recombinant surfactant protein C (rSP-C)-based surfactant results in improvement in blood oxygenation and have suggested that treatment of patients with severe direct lung injury may decrease mortality. - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. Bates, PhD, DSc Research Professor of Medicine. •Surfactant is a surface acting material or agent that is responsible for lowering the surface tension of a fluid. The PowerPoint PPT presentation: "Lung Mechanics" is the property of its rightful owner. If so, share your PPT presentation slides online with PowerShow.com. According to various pathogenetic mechanisms and aetiologies, PAP is classified as primary, secondary or congenital. Toti P, Buonocore G, Rinaldi G, Catella AM, Bracci R. Pulmonary pathology in surfactant-treated preterm infants with respiratory distress syndrome: An autopsy study. Bronchoalveolar lavage (BAL) fluid … Surfactant replacement therapy in preterm neonates: A comparison of postmortem pulmonary histology in treated and untreated infants. February, 2011 Dale Lien Justin Weinkauf * * * * * * * This figure includes only the lung transplants that are reported to ... - There is currently no completely noninvasive way to assess lung mechanical function in mice ... why chamber pressure varies as a mouse breathes? - Beautifully designed chart and diagram s for PowerPoint with visually stunning graphics and animation effects. Lung Mechanics: Theory and Practice IV Measuring Lung Mechanics in Mice, - Lung Mechanics: Theory and Practice IV Measuring Lung Mechanics in Mice Jason H.T. Current influenza vaccines only confer protection against homologous viruses. Flow. The mixture is surface active and acts to decrease surface tension at the air–liquid interface of the alveoli. And they’re ready for you to use in your PowerPoint presentations the moment you need them. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. - Lung Mechanics: Theory and Practice I. Bates, PhD, DSc Research Professor of Medicine Vermont Lung Center, - Title: Targeted Therapies for Advanced Non-Small Cell Lung Cancer Author: Can Ozturk Last modified by: CAN OZTURK Created Date: 9/29/2005 4:26:22 AM, Lung Mechanics: Theory and Practice I The Basics of Measuring Lung Mechanics. Pulmonary surfactant has both protein and lipid components. The surface tension between gaseous- aqueous interphase in the lungs is decreased by the presence of a thin layer of fluid known as pulmonary surfactant. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Pulmonary alveolar proteinosis (PAP) is a rare respiratory syndrome characterised by the accumulation of surfactant lipoproteins within the alveoli. Some new synthetic surfactants containing protein analogues, including CHF5633, have recently been studied. Pulmonary alveolar proteinosis is a rare but potentially treatable disease, characterized by impaired surfactant metabolism that leads to accumulation in the alveoli of proteinaceous material rich in surfactant protein and its component. - Lung Transplantation: Where Are We in 2011? It is formed by type II pneumocytes from about 20 weeks of gestation. - Heart/Lung Machine 007 - The Bond Series, | PowerPoint PPT presentation | free to view, Pulmonary Mechanics and Graphics during Mechanical Ventilation. ... RADIOLOGICAL EXAMINATION OF THE LUNG AND PLEURA. Or use it to create really cool photo slideshows - with 2D and 3D transitions, animation, and your choice of music - that you can share with your Facebook friends or Google+ circles. Pathology. Pulmonary surfactant is a complex mixture of phospholipids, neutral lipids, and specific proteins; it is produced by the alveolar type II epithelial cell (AEC2), stored in intracellular organelles known as lamellar bodies, and secreted by exocytosis into the alveolar lumen. Pulmonary surfactant is a complex of highly active phospholipids and proteins that cover the alveolar epithelial surface of the lungs 1. Whether your application is business, how-to, education, medicine, school, church, sales, marketing, online training or just for fun, PowerShow.com is a great resource. 1. 1. - Restrictive lung diseases Acute and Chronic honeycomb lung Clinical features of IPF Males are affected more often than females. The source(s) … The mixture is surface active and acts to decrease surface tension at the air–liquid interface of the alveoli. Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Objectives To reprogram non-small cell lung cancer (NSCLC) ... - Measuring Neonatal Lung Volume Advisor: Dr. Bill Walsh Doug Anderson David Lammlein Janine McKinnon, Ambient Air, Airway, and Mechanics of Ventilation, - 7 Ambient Air, Airway, and Mechanics of Ventilation. Other advantages are that radiography and epifluorescent microscopy of the surface f… Pulmonary endothelial and alveolar epithelial injury permeability edema Surfactant dysfunction Maladaptive repair with mesenchymal cells and proliferative fibroblasts Alveolar edema and proteins are cleared, endothelial and epithelial injury repaired Acute hypoxemia, Increased dead space Venous admixture (V/Q mismatch) Low compliance Pulmonary We aimed to analyze the compositional changes in the surfactant lipidome in COPD and identify specific lipids associated with pulmonary function decline. t1. According to LaPlaces law, the pressure (P) necessary to keep the sphere open is proportional to the surface tension (T) and inversely proportional to the radius (R) of the sphere, shown by the formula P = 2T/R If … 1). Surfactant proteins. t3. 1... VentilationPerfusion Relationships in the Lung. The interaction between drug molecules and pulmonary surfactants affects the efficacy of the drug directly. Pulmonary surfactant is a surface-active lipoprotein complex formed by type II alveolar cells.The proteins and lipids that comprise surfactant have both a hydrophilic region and a hydrophobic region. - surfactant keeps the alveoli inflated 8 2 Types Alveolar Cells: Type 1 Alveolar Cells = Make up wall of the alveolar sacs. Type 2 Alveolar Cells - secrete surfactant Surfactant = substance that decreases surface … Surfactant is an agent that decreases the surface tension between two media. List the surfactant proteins. What are surfactant proteins covered by? Lung Compliance Lung compliance (CL) is a measure of the elastic properties of the lung ... - Mechanics of Breathing Breathing Inspiration: ... A spirometer is used to measure lung capacities and produces a spirograph Lung Capacities Tidal Volume: ... Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells. Many of them are also animated. Pulmonary administration is widely used for the treatment of lung diseases. More specifically, it has been found that phosphatidylcholine (PC) is the most abundant phospholipid (70%–85%), and that PC is primarily present as dipalmitoylphosphatidylcholine (DPPC). The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions. CrystalGraphics 3D Character Slides for PowerPoint, - CrystalGraphics 3D Character Slides for PowerPoint. Physiologic concepts. In this method, the surface tension at an air/water interface is directly measured by a small plate attached to an electro balance. Overview. Pulmonary surfactant is produced by cells within the lungs and decreases surface tension by breaking bonds between water molecules. During lung injury, fibroblasts migrate into the alveolar spaces where they can be exposed to pulmonary surfactant. We examined the effects of Survanta and surfactant protein A (SP-A) on fibroblast growth and apoptosis and on type I collagen, collagenase-1, and tissue … Pulmonary surfactant is made by our lungs and decreases the surface tension so we can breathe. - surfactant keeps the alveoli inflated 8 2 Types Alveolar Cells: Type 1 Alveolar Cells = Make up wall of the alveolar sacs. The major lipid present in pulmonary surfactant is phosphatidylcholine (PC), a large fraction of which contains two palmitic acid side chains … Pulmonary surfactant is a specialized biological fluid synthesized and secreted by ___ alveolar cells. Reason No. Surfactant was the first drug developed solely for treatment of neonates; a major breakthrough in neonatal medicine in the past 35 years. Primary PAP is led by a granulocyte–macrophage colony-stimulating factor (GM-CSF) signalling disruption; the autoimmune … A mixture of phospholipids and protein... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 120db9-NjIzO Type 2 Alveolar Cells - secrete surfactant Surfactant = substance that decreases surface … And, best of all, most of its cool features are free and easy to use. - Part 2 Mechanical Properties of the Lung and Chest Wall: Static and Dynamic 2. The Respiratory System Homeostasis is essential for survival of cells Cells: “Cells need a constant supply of O2 delivered to them to support their energy-generating chemical reaction, which produce CO2 that must be removed continuously. … Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. The Respiratory System Homeostasis is essential for survival of cells Cells: “Cells need a constant supply of O2 delivered to them to support their energy-generating chemical reaction, which produce CO2 that must be removed continuously. Lung Transplantation: Where Are We in 2011? Summary Pulmonary surfactant is a complex mixture of specific lipids, proteins and carbohydrates, which is produced in the lungs by type II alveolar epithelial cells. Overview. M1a = Separate tumor nodule(s) in a contralateral lobe tumor with pleural nodules or ... Part 2 Mechanical Properties of the Lung and Chest Wall: Static and Dynamic. t2. Smoke exposure is known to decrease total pulmonary surfactant and alter its composition, but the role of surfactant in chronic obstructive pulmonary disease (COPD) remains unknown. A mixture of phospholipids and protein ... – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 120db9-NjIzO. It is formed by type II pneumocytes from about 20 weeks of gestation. Northway WH. Surfactant is synthesized in the alveolar type-II cells, stored in the lamellar bodies, and secreted to the alveolar space where it undergoes complex changes 2. Type II. Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. Pediatr Pathol 1994;14:945-53. The surface tension between gaseous- aqueous interphase in the lungs is decreased by the presence of a thin layer of fluid known as pulmonary surfactant. Pulmonary surfactant represents a complex mixture of what? PowerShow.com is a leading presentation/slideshow sharing website. Integration of flow. •SpA •SpB •SpC •SpD. The pulmonary surfactant is produced by the alveolar type-II … Pulmonary surfactant is a surface-active lipoprotein complex formed by type II alveolar cells.The proteins and lipids that comprise surfactant have both a hydrophilic region and a hydrophobic region. See our Privacy Policy and User Agreement for details. - Introduce additional lung units with mismatch between V and Q ... Hyperventilation defined as PACO2 40. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. If you continue browsing the site, you agree to the use of cookies on this website. The assembly of the surfactant proteins into lamellar bodies is less clear and may proceed via the endoplasmic reticulum and Golgi apparatus to multivesicular bodies before combining with the lamellar bodies (10). Looks like you’ve clipped this slide to already. * Staging 6 M0 = No distant metastasis. Type II epithelial cells synthesize and assemble the lipid and protein components into complexes that are stored as tightly packed membranes in lamellar bodies until secreted into the … By adsorbing to the air-water interface of alveoli, with hydrophilic head groups in the water and the hydrophobic tails facing towards the air, the main lipid component of surfactant, dipalmitoylphosphatidylcholine (DPPC), reduces surface tension. Clinical : ... Embryology. World's Best PowerPoint Templates - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. Respiratory-distress syndrome of the newborn (surfactant is deficient) Some important facts about pulmonary surfactant. Anatomic concepts. 6 breastfeeding and drugs and acceptable medical reasons for artificial feedi... No public clipboards found for this slide. Pulmonary surfactant is a complex mixture of phospholipids and proteins that serves to reduce alveolar surface tension. It's FREE! Direct measurement with a spirometer. Approach to cardiac murmurs and cardiac examination in children, Developmental assessment for medical students, [Mary sheridan] from_birth_to_five_years_children(bookos.org)[1], 7 breastfeeding the premature and the sick term baby. Clipping is a handy way to collect important slides you want to go back to later. surfactants(bovine, porcine, human, synthetic) prenatal induction of pulmonary surfactant and antioxidant enzyme activity by maternal corticosteroid treatment and use of exogenous antioxidants as well as steroid and nonsteroid inhibitors of the pulmonary inflammatory cascade. Bronchopulmonary dysplasia Twenty-five Years Later. See our User Agreement and Privacy Policy. The pulmonary surfactant is produced by the alveolar type-II … Decreasing V/Q produces lower PAO2 and higher PACO2. One of the major advantages of this system is that a well-defined monolayer of lipids and proteins can be spread at the air/liquid surface. The PL are assembled in the endoplasmic reticulum and the Golgi apparatus of alveolar type II cells and are stored in lamellar bodies until exocytosis (Fig. 18. It’s 97% of total lung surface area where most gas exchange occurs. It’s 97% of total lung surface area where most gas exchange occurs. B. Pulmonary surfactant is a complex mixture of phospholipids (PL), neutral lipids [particularly cholesterol (Chol)], and proteins. - The lung and the Upper Respiratory Tract -1 Atelectasis Obstructive Lung Disease Thoracic Assessment Breath Sounds absent or decreased Atelectasis: Pneumothorax ... - Toxic responses of the lung Environmental health and toxicology Lecture 7 Lecture Objectives Content Respiratory system Stages of lung toxic responses Workplace ... - Embryology. Now customize the name of a clipboard to store your clips. Novel insights from an animal model aided the discovery of granulocyte macrophage colony stimulating factor (GM-CSF) antibodies as a pathogenetic mechanism … •Surfactant that lines the epithelium of the alveoli in lungs is known as pulmonary surfactant and it decreases the surface tension on the alveolar membrane. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. The Basics of Measuring Lung ... A. One of the first model systems used to examine surface activity of several surfactant components was the LangmuirWilhelmy balance, introduced by Clements [81]. presentations for free. Furthermore, CO2 generates carbonic acid with which the body must continuously deal in order to maintain the proper pH in the internal environment. Or use it to upload your own PowerPoint slides so you can share them with your teachers, class, students, bosses, employees, customers, potential investors or the world. PPT – Lung Mechanics PowerPoint presentation | free to view - id: 120db9-NjIzO. Summary Pulmonary surfactant is a complex mixture of specific lipids, proteins and carbohydrates, which is produced in the lungs by type II alveolar epithelial cells. Do you have PowerPoint slides to share? That's all free as well! Surfactant in Preterm Infants Introduction Pulmonary surfactant is a complex mixture of phospholipids and proteins that serves to reduce alveolar surface tension. Pulmonary surfactant (PS) replacement therapy has been established as a safe and effective treatment for immaturity-related surfactant deficiency since the early 1990s. The major components of pulmonary surfactant include phospholipids (∼80%), neutral lipids (mainly cholesterol, ∼10%), and the two hydrophobic peptides (1–2%) surfactant protein B (SP-B) and SP-C. Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. SURFACTANT 2. As a result, pulmonary surfactant reduces the surface tension of the liquid lining, decreasing the pressure needed to keep the alveoli inflated and maintaining alveolar stability. Surfactant (Physiology) 1. Furthermore, CO2 generates carbonic acid with which the body must continuously deal in order to maintain the proper pH in the internal environment. Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. If you continue browsing the site, you agree to the use of cookies on this website. There is a significant disturbance of the pulmonary surfactant system in MAS, with a wealth of experimental data indicating that inhibition of surfactant function in the alveolar space is an important element of the pathophysiology of the disease. Pulmonary surfactant is a complex mixture of lipids and proteins that reduces surface tension at the interface between air and liquid. Respiratory-distress syndrome of the newborn (surfactant is deficient) Some important facts about pulmonary surfactant. Lung Mechanics: Theory and Practice V Lung Mechanics in Mouse Models of Pulmonary Disease, - Lung Mechanics: Theory and Practice V Lung Mechanics in Mouse Models of Pulmonary Disease Jason H.T. - Pulmonary Mechanics and Graphics during Mechanical Ventilation Definition Mechanics: Expression of lung function through measures of pressure and flow: Derived ... - New treatment options for lung cancer Lung cancer is a leading cause of death world wide 90% of lung cancer is caused by smoking 20% of patients are suitable for ... - Radiofrequency Ablation of Lung Cancer Andrew R. Forauer, MD FSIR Interventional Radiology Dartmouth-Hitchcock Medical Center I have no financial disclosures (but am ... - Lung cancer Edit Csada MD 08.10.2014. 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